Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2109050 | Cancer Epidemiology | 2012 | 5 Pages |
Abstract
Our result demonstrate for the first time that CHEK2 1100delC, IVS2+1G>A and I157T mutations have not been agenetic susceptibility factor for CRC in the Turkish population. Overall, our data suggest that genotyping of CHEK2 mutations in clinical settings in the Turkish population should not be recommended. However, independent studies are need to validate our findings in a larger series, as well as in patients of different ethnic origins.
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Authors
Süleyman Bayram, Mehmet TopaktaÅ, Hikmet Akkız, Aynur Bekar, Ersin Akgöllü,