Article ID Journal Published Year Pages File Type
2111685 Cancer Genetics and Cytogenetics 2007 4 Pages PDF
Abstract
The t(2;11)(q37;q23) is a rare recurrent cytogenetic abnormality associated with de novo and therapy-related acute myeloid leukemia, resulting in a MLL-SEPT2 fusion gene. We report on a case of therapy-related acute myeloid leukemia M2 showing a t(2;11)(q37;q23) and resulting in a new subtype of a MLL-SEPT2 chimeric transcript. The literature on this translocation is reviewed.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
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A new subtype of MLL-SEPT2 fusion transcript in therapy-related acute myeloid leukemia with t(2;11)(q37;q23): a case report and literature review
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