| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2113554 | Cancer Letters | 2011 | 7 Pages |
Abstract
⺠We developed an automatic method to detect mutations observed in imatinib-resistance. ⺠The method utilizes guanine-quenching probes (QP). ⺠Seventeen mutations can be detected automatically. ⺠Detected mutations were almost identical between QP method and direct sequencing. ⺠We improved the sensitivity with mutation-biased PCR.
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Authors
Ruriko Tanaka, Shinya Kimura, Eishi Ashihara, Mariko Yoshimura, Naoto Takahashi, Hisashi Wakita, Kuniaki Itoh, Kaichi Nishiwaki, Kenshi Suzuki, Rina Nagao, Hisayuki Yao, Yoshihiro Hayashi, Sakiko Satake, Hideyo Hirai, Ken-ichi Sawada, Oliver G. Ottmann,