Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2114083 | Cancer Letters | 2010 | 4 Pages |
Abstract
The aquaporins (AQPs) are a family of transmembrane water channel proteins widely distributed and play a major role in transcellular and transepithelial water movement. Moreover, recent evidence indicates that AQPs may be involved in cell migration and angiogenesis. This review article summarizes literature data concerning the involvement of AQPs in tumor growth, angiogenesis and metastatic process and suggest a potential therapeutic approach by antagonizing their biological activity.
Keywords
Related Topics
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Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Beatrice Nico, Domenico Ribatti,