Article ID Journal Published Year Pages File Type
2114083 Cancer Letters 2010 4 Pages PDF
Abstract

The aquaporins (AQPs) are a family of transmembrane water channel proteins widely distributed and play a major role in transcellular and transepithelial water movement. Moreover, recent evidence indicates that AQPs may be involved in cell migration and angiogenesis. This review article summarizes literature data concerning the involvement of AQPs in tumor growth, angiogenesis and metastatic process and suggest a potential therapeutic approach by antagonizing their biological activity.

Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
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