Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2114953 | Cancer Letters | 2008 | 6 Pages |
Abstract
The oxidation potentials of fifteen flavonoids in phosphate buffer at pH 7.2 were determined by cyclic voltammetry. A good correlation was found between these oxidation potentials and the ability of flavonoids to inhibit Epstein–Barr virus early antigen (EBV-EA) activation. Furthermore, multiple regression analysis revealed that the solvent-accessible surface area (SASA) was a useful parameter for estimating the inhibitory effects of flavonoids on EBV-EA activation.
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Authors
Junko Koyama, Izumi Morita, Norihiro Kobayashi, Takao Konoshima, Midori Takasaki, Toshiyuki Osakai, Harukuni Tokuda,