Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2115127 | Cancer Letters | 2007 | 5 Pages |
Abstract
Under standard culture conditions, tumor cells are exposed to 20% O2, whereas the mean tumor oxygen levels within the tumor are much lower. We demonstrate, using low-passaged human tumor cell cultures established from glioma, that a reduction in the oxygen level in these cell cultures dramatically increases the percentage of CD133 expressing cells.
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Authors
Nadine Platet, Shi Yong Liu, Michèle El Atifi, Lisa Oliver, François M. Vallette, François Berger, Didier Wion,