Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2115803 | Cancer Letters | 2006 | 5 Pages |
Abstract
We have previously reported a reduction in the accumulation of ascitic fluid in Ehrlich tumor-bearing mice following treatment with the powdered roots of Pfaffia paniculata [1]. The aim of this study was to investigate which extracts from these roots presented antineoplastic properties. Thus, the effects of the ethanolic extract, butanolic residue, or aqueous residue from Pfaffia paniculata on animal survival and tumor growth in mice bearing this tumor were studied. Butanolic residue-treated mice survived longer than untreated mice. This result points to an antineoplastic effect exerted by the butanolic fraction from the roots of P. paniculata on this tumor model.
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Authors
Patrícia Matsuzaki, Mitsue Haraguchi, Gokithi Akisue, Sílvia Catarina Salgado Oloris, Márcia Kazumi Nagamine, Tereza Cristina da Silva, Monica Sakai, Evelise de Souza Monteiro Fonseca, João Palermo-Neto, Silvana Lima Górniak, Maria Lúcia Zaidan Dagli,