| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2123630 | European Journal of Cancer | 2010 | 8 Pages |
Abstract
This is the first demonstration that the loss of TIMP3 expression is observed in almost all CCRCCs. This loss of expression is a common molecular event in CCRCC. It may be an important initiation step for tumour development in a complex process implicating loss of heterozygosity on chromosome 22q, promoter hyper-methylation and inactivation of the TGFβRII pathway.
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Authors
Damien Masson, Nathalie Rioux-Leclercq, Patricia Fergelot, Florence Jouan, Stéphanie Mottier, Sandrine Théoleyre, Kalyane Bach-Ngohou, Jean-Jacques Patard, Marc G. Denis,