Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2124041 | European Journal of Cancer | 2010 | 7 Pages |
Abstract
For ER positive tumours in the 50-64 age group, age-standardised rates increased 31.5% from 1997 to 2000, followed by a statistically significant decrease of 11.2% by 2005 (change in slope = â0.0943, P < 0.0001). We conclude that an overall incidence in the 50-64 age group declined since 2000 reflecting the sudden fall in HRT dispensed items and is largely accounted for by the decrease in ER positive tumour incidence. A longer term decline in ER negative tumours for this age group was pre-existing and is unaffected by the collapse in HRT prescribing.
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Authors
Katharine H. Sharpe, Paula McClements, Douglas I. Clark, Joanne Collins, Anthea Springbett, David H. Brewster,