Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2125624 | European Journal of Cancer | 2007 | 8 Pages |
Abstract
Through the analysis of the specialised literature and a set of original epidemiological and biological data concerning retinoblastoma, the authors illustrate the evidences arguing against the 'two hit' hypothesis and propose that epigenetic factors and aneuploidy play central roles in the disease.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
D. Mastrangelo, S. De Francesco, A. Di Leonardo, L. Lentini, T. Hadjistilianou,