Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2129996 | Experimental Cell Research | 2016 | 10 Pages |
Abstract
•3D cell culture spheroids mimic the tumor microenvironment.•Aptamers selected in 3D cell culture is ideal for discovery of novel markers.•Small aptamers with spontaneous folding (−∆G) were enriched against tumor spheroids.•Aptamers may be used as potential markers for prostate cancer.
Human prostate cancer (PCa)
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Authors
Aline G. Souza, Karina Marangoni, Patrícia T. Fujimura, Patrícia T. Alves, Márcio J. Silva, Victor Alexandre F Bastos, Luiz R. Goulart, Vivian A. Goulart,