Article ID Journal Published Year Pages File Type
2130533 Experimental Cell Research 2012 13 Pages PDF
Abstract
► Melanogenesis stimulation by l-tyrosine+NH4Cl in B16-F10 melanoma cells increases ROS levels. ► Melanogenesis inhibits cell proliferation, and induced cell cycle arrest in the G1 phase. ► Proteomic analysis showed alterations in proteins of the cell cycle and glucose metabolism. ► RT-qPCR analysis confirmed alterations of metabolic targets after melanogenesis stimulation.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Preview
Melanogenesis stimulation in B16-F10 melanoma cells induces cell cycle alterations, increased ROS levels and a differential expression of proteins as revealed by proteomic analysis
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