| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2130614 | Experimental Cell Research | 2012 | 7 Pages |
Abstract
The synaptonemal complex (SC) is a proteinaceous structure of chromosome bivalents whose assembly is indispensable for the successful progression of the first meiotic division of sexually reproducing organisms. In this mini-review we will focus on recent progress dealing with the composition and assembly of the mammalian SC. These advances mainly resulted from the systematic use of knockout mice for all known mammalian SC proteins as well as from protein polymerization studies performed in heterologous systems.
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Authors
Johanna Fraune, Sabine Schramm, Manfred Alsheimer, Ricardo Benavente,