Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2130735 | Experimental Cell Research | 2012 | 8 Pages |
Abstract
⺠We used dorsal root ganglia neuron culture as experimental model. ⺠We investigated the biological effects of NRG1 with particular emphasis on neurite growth. ⺠We tested the effects of NRG1 treatment in comparison to NGF and control conditions. ⺠NRG1 induces the growth of fewer but longer neurites in comparison to NGF treatment. ⺠The effects of NRG1 on neurite outgrowth could be partially mediated by NGF release.
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Authors
Chiara Audisio, Cristina Mantovani, Stefania Raimondo, Stefano Geuna, Isabelle Perroteau, Giorgio Terenghi,