Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2130744 | Experimental Cell Research | 2012 | 8 Pages |
Abstract
⺠Upregulation of tescalcin gene augments megakaryocyte development in K562 and HEL cells. ⺠Mice with targeted disruption of tescalcin gene were created. ⺠Platelet and megakaryocyte numbers are normal in tescalcin-knockout mice. ⺠Polyploidization and Fli-1 expression in megakaryocytes of tescalcin-knockout mice is normal. ⺠Tescalcin does not have an essential role in megakaryocyte differentiation in a murine model.
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Authors
Supamit Ukarapong, Yong Bao, Erasmo M. Perera, Gary D. Berkovitz,