Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2133898 | Experimental Hematology | 2011 | 12 Pages |
Abstract
Our results indicate that endogenous CD26 normally suppresses megakaryopoiesis and that loss of CD26 activity results in expansion of the megakaryocyte progenitor population in vivo. This suggests the potential use of CD26 inhibitors to improve megakaryocyte progenitor function and/or reconstitution of the megakaryocyte cell population.
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Authors
Shannon Kidd, Carlos Bueso-Ramos, Sucheta Jagan, Laura A. Paganessi, Lisa N. Boggio, Henry C. Fung, Stephanie A. Gregory, Kent W. II,