Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2134365 | Experimental Hematology | 2011 | 17 Pages |
Abstract
These data demonstrate that the Flt3-ITD confers sensitivity to Ara-C, but resistance to doxorubicin in a manner that depends on p53. Thus, patients with Flt3-ITD positive AML may not benefit from treatment with an anthracycline.
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Authors
Timothy S. Pardee, Johannes Zuber, Scott W. Lowe,