Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2134487 | Experimental Hematology | 2010 | 11 Pages |
Abstract
The DPP2 apoptosis assay provides a reliable prognostic factor in CLL. CLL B cells sensitive to DPP2 inhibition are in true G0, while resistant CLL B-cells are partially activated. DPP2 inhibition alone or with concomitant inhibition of heat shock protein 90 warrants investigation as a therapeutic modality in CLL.
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Authors
Alexey V. Danilov, Olga V. Danilova, Jennifer R. Brown, Arthur Rabinowitz, Andreas K. Klein, Brigitte T. Huber,