Article ID Journal Published Year Pages File Type
2134487 Experimental Hematology 2010 11 Pages PDF
Abstract
The DPP2 apoptosis assay provides a reliable prognostic factor in CLL. CLL B cells sensitive to DPP2 inhibition are in true G0, while resistant CLL B-cells are partially activated. DPP2 inhibition alone or with concomitant inhibition of heat shock protein 90 warrants investigation as a therapeutic modality in CLL.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
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