Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2134592 | Experimental Hematology | 2010 | 13 Pages |
Abstract
The miR-23a cluster is a downstream target of PU.1 involved in antagonizing lymphoid cell fate acquisition. Although miRNAs have been identified downstream of PU.1 in mediating development of monocytes and granulocytes, the 23a cluster is the first downstream miRNA target implicated in regulating development of myeloid vs lymphoid cells.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Kimi Y. Kong, Kristin S. Owens, Jason H. Rogers, Jason Mullenix, Chinavenmeni S. Velu, H. Leighton Grimes, Richard Dahl,