| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2134748 | Experimental Hematology | 2010 | 10 Pages |
Abstract
Our results indicate that ET monocytes are responsible for sIL-6R overproduction within mononuclear cells through synthesis upregulation. In addition, the lack of cooperation of lymphocytes in monocyte sIL-6R production in ET could be due to a monocyte abnormality. The agonistic effect of sIL-6R on IL-6 action could contribute to the exacerbated megakaryocytic growth in ET.
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Authors
Nora P. Goette, Paola R. Lev, Paula G. Heller, Ana C. Glembotsky, Carlos D. Chazarreta, Juan P. Salim, Felisa C. Molinas, Rosana F. Marta,