| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2134756 | Experimental Hematology | 2010 | 12 Pages |
Abstract
MSCs induced an allograft response in rhesus macaques that involved principally CD8+, CD16+, and CD8+/CD16+ lymphocyte subpopulations and was cell-doseâ and haplotype-dependent. This study demonstrates that MSCs are weakly immunogenic in vivo when transplanted across MHC class I barriers.
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Authors
Iryna A. Isakova, Jason Dufour, Calvin Lanclos, Julie Bruhn, Donald G. Phinney,