Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2134934 | Experimental Hematology | 2009 | 9 Pages |
Abstract
This is one of the first reports to show that changes in DNA methylation patterns across large domains around non-CpG island genes correspond with changes in developmentally regulated histone modifications and gene expression. These data support a new model in which extended domains of DNA hypomethylation and active histone marks are coordinately established to achieve developmentally specific gene expression of non-CpG island genes.
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Authors
Melissa J. Lathrop, Mei Hsu, Christine A. Richardson, Emmanuel N. Olivier, Caihong Qiu, Eric E. Bouhassira, Steven Fiering, Christopher H. Lowrey,