Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2134938 | Experimental Hematology | 2009 | 11 Pages |
Abstract
Our data suggest that reduction in the proportion of γδ T cells and granzyme B gene polymorphism leads to defective immune function in breast cancer patients. Treatment with zoledronic acid amend partially this fault. Further studies of γδ T cells function and granzyme B gene polymorphism in cancers, as well as the potential therapeutic use of zoledronic acid are warranted.
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Cancer Research
Authors
Ameera Gaafar, Mahmoud Deeb Aljurf, Abdullah Al-Sulaiman, Alia Iqniebi, Pulicat S. Manogaran, Gamal Eldin H. Mohamed, Adher Al-Sayed, Hazaa Alzahrani, Fahad Alsharif, Fahad Mohareb, Dahish Ajarim, Abdelghani Tabakhi, Khalid Al-Hussein,