Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2134940 | Experimental Hematology | 2009 | 12 Pages |
Abstract
Reciprocal expression of Bmi1 and Mel-18 regulated HSC function. Here, we observed that expression of the PcG genes-bmi1 and mel-18-is correlated with self-renewal and differentiation of HSCs. Thus, it was suggested that the balance between Bmi1 and Mel-18 regulates self-renewal of HSCs.
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Authors
Teruyuki Kajiume, Norioki Ohno, Yasuhiko Sera, Yumi Kawahara, Louis Yuge, Masao Kobayashi,