Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2135003 | Experimental Hematology | 2009 | 18 Pages |
Abstract
This is the first time that a small-molecule c-MPL agonist has been demonstrated to promote net expansion of HSCs. NR-101 is more efficient in ex vivo expansion of HSCs than TPO. NR-101 could be a useful tool for the therapeutic manipulation of human HSCs.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Taito Nishino, Katsuaki Miyaji, Norihisa Ishiwata, Kazutaka Arai, Makiko Yui, Yasuyuki Asai, Hiromitsu Nakauchi, Atsushi Iwama,