Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2135037 | Experimental Hematology | 2008 | 15 Pages |
Abstract
Our results provide the first evidence that BM endothelial cells promote expansion of hematopoietic progenitor cells by a Notch-dependent mechanism and that TNF-α and LPS can modulate the levels of Notch ligand expression and Notch activation in the BM microenvironment in vivo.
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Authors
Luis Fernandez, Sonia Rodriguez, Hui Huang, Angelo Chora, Jacquenilson Fernandes, Christin Mumaw, Eugenia Cruz, Karen Pollok, Filipa Cristina, Joanne E. Price, Michael J. Ferkowicz, David T. Scadden, Matthias Clauss, Angelo A. Cardoso, Nadia Carlesso,