Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2135319 | Experimental Hematology | 2007 | 12 Pages |
Abstract
We demonstrate that ectopic expression of PU.1 is sufficient to immortalize a hematopoietic progenitor with myeloid and erythroid differentiation potential in response to GM-CSF. These data highlight the importance of the level of PU.1 expression at critical stages of hematopoiesis.
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Authors
Isaac B. Houston, Kelly J. Huang, Serena R. Jennings, Rodney P. DeKoter,