Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2136554 | Leukemia Research | 2015 | 9 Pages |
Abstract
•Heme oxygenase-1 (HO-1) is aberrantly overexpressed in the majority of AML patients.•HO-1 has an effect on the apoptosis of AML cell lines.•Overexpression of HO-1 accelerates leukemia's progression in vivo.•HO-1 suppresses the apoptosis of AML cells through activating JNK/c-JUN signaling pathway.
There are few studies on the correlation between heme oxygenase-1 (HO-1) and acute myeloid leukemia (AML). We found that HO-1 was abe
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Authors
Xiaojing Lin, Qin Fang, Shuya Chen, Nana Zhe, Qixiang Chai, Meisheng Yu, Yaming Zhang, Ziming Wang, Jishi Wang,