Article ID Journal Published Year Pages File Type
2136554 Leukemia Research 2015 9 Pages PDF
Abstract

•Heme oxygenase-1 (HO-1) is aberrantly overexpressed in the majority of AML patients.•HO-1 has an effect on the apoptosis of AML cell lines.•Overexpression of HO-1 accelerates leukemia's progression in vivo.•HO-1 suppresses the apoptosis of AML cells through activating JNK/c-JUN signaling pathway.

There are few studies on the correlation between heme oxygenase-1 (HO-1) and acute myeloid leukemia (AML). We found that HO-1 was abe

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