Article ID Journal Published Year Pages File Type
2136599 Leukemia Research 2015 14 Pages PDF
Abstract

•Generation of miR-155 network on FLT3-ITD+ AML utilizing data from multiple sources.•Connections among miR-155 and master myeloid transcription factor in FLT3-ITD+ AML.•Inhibition of FLT3-ITD decreases p-JUN and miR-155 and increases miR-155 targets.•Inverse correlation between miR-155 and TFs (PU.1 and CEBP-beta) in FLT3-ITD+ AML.•In vitro functional ex

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