| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2136986 | Leukemia Research | 2014 | 5 Pages |
Abstract
The prognostic significance of extra-medullary chronic lymphocytic leukemia (EM-CLL) is unknown. We conducted a Medline database systematic search analyzing English language articles published between 1975 and 2012 identifying 192 cases. Patients with EM-CLL were more commonly treated than not (p < .001). Skin and central nervous system (CNS) were the most commonly reported sites of organ involvement. Survival after diagnosis of EM-CLL appeared to depend on the site of EM involvement. Prospective evaluation and further studies of EM-CLL are warranted.
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Authors
Megan Ratterman, Kimberly Kruczek, Suela Sulo, Tait D. Shanafelt, Neil E. Kay, Chadi Nabhan,