| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2137721 | Leukemia Research | 2009 | 4 Pages |
Abstract
Tumor cells are surrounded by an infiltrate of inflammatory cells, namely lymphocytes, neutrophils, macrophages and mast cells (MCs). Increasing evidence indicates that MCs play a role in tumor growth and tumor-related angiogenesis in both solid and haematological tumors. In this review article, we discuss the involvement of MCs in angiogenesis in haematological malignancies and suggest that MCs might act as a new target for the adjuvant treatment of these tumors through the selective inhibition of angiogenesis.
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Authors
Domenico Ribatti, Enrico Crivellato, Stefano Molica,