| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2138273 | Leukemia Research | 2010 | 6 Pages |
Abstract
The intracellular expression of Smac/DIABLO protein was assessed using multi-color flow cytometry in 71 newly diagnosed AML patients treated with conventional chemotherapy. It was found that the high expression of Smac/DIABLO protein was an independent prognostic factor in terms of higher complete remission rate (p < 0.001) and longer overall survival (p = 0.003). Moreover the low expression of Smac/DIABLO protein was associated with poor karyotype.
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Authors
Agnieszka Pluta, Agata Wrzesien-Kus, Barbara Cebula-Obrzut, Anna Wolska, Anna Szmigielska-Kaplon, Magdalena Czemerska, Piotr Pluta, Tadeusz Robak, Piotr Smolewski, Agnieszka Wierzbowska,