Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2138339 | Leukemia Research | 2009 | 5 Pages |
Abstract
Hemorrhagic cystitis is a common complication in hematopoietic stem cell transplant recipients. We report here a case of severe BKV-associated hemorrhagic cystitis who did not respond to intravenous cidofovir. Overt hematuria successfully resolved after a few days on hyperbaric oxygen and intravesical instillations of cidofovir, while BK viruria dropped after a few weeks and remained low. We review the literature for therapeutic options in hemorrhagic cystitis and try to explain how hyperbaric oxygen stimulates mucosal repair in the urinary bladder.
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Authors
Daniele Focosi, Fabrizio Maggi, Donatella Pistolesi, Edoardo Benedetti, Federico Papineschi, Sara Galimberti, Luca Ceccherini-Nelli, Mario Petrini,