Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2140475 | Lung Cancer | 2016 | 7 Pages |
Abstract
Our RT-qPCR assay demonstrates that the capability and reliability of ALK detection is comparable to FISH and IHC, but it is more effective at discriminating ALK rearrangement from overexpression. The RT-qPCR assay easily clarifies the discrepancy between FISH and IHC, and can be incorporated into routine ALK screening for lung cancer.
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Authors
Jrhau Lung, Yu-Ching Lin, Ming-Szu Hung, Yuan Yuan Jiang, Kuan-Der Lee, Paul Yann Lin, Ying Huang Tsai,