Article ID Journal Published Year Pages File Type
2143297 Lung Cancer 2009 7 Pages PDF
Abstract

SummaryBackgroundATP-binding cassette (ABC) transporter and DNA excision repair proteins play a pivotal role in the mechanisms of drug resistance. The aim of this study was to investigate the expression of ABC transporter and DNA excision repair proteins, and to elucidate the clinical significance of their expression in biopsy specimens from patients with small-cell lung cancer (SCLC).MethodsWe investigated expression of the ABC transporter proteins, P-glycoprotein (Pgp), multidrug resistance associated-protein 1 (MRP1), MRP2, MR

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Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
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