Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2144118 | Lung Cancer | 2006 | 5 Pages |
Abstract
SummarySecretion of ectopic adrenocorticotropic hormone (ACTH) with consequently Cushing's syndrome is a rare paraneoplastic phenomenon. It has been described in a variety of malignancies, like bronchial carcinoids, small-cell lung carcinoma, thymoma, pancreatic carcinoma and other. In many cases of suspected ectopic ACTH secretion, it is difficult to histologically or cytochemically confirm the diagnosis. We present a 63-year-old woman with a recurrent poorly differentiated squamous cell lung carcinoma with clinical and biochemical features consistent with ectopic Cushing's syndrome. Immunocytochemical staining confirmed the secretion of ACTH by tumour cells.
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Authors
I. Noorlander, J.W. Elte, O.C. Manintveld, K.G. Tournoy, M.M. Praet, J.P. van Meerbeeck, J.G. Aerts,