| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2144850 | Matrix Biology | 2012 | 9 Pages |
Abstract
⺠We modeled prostate cancer cell-bone matrix interactions in vitro. ⺠Osteonectin-null bone matrix was disorganized. ⺠Osteonectin-null bone matrix promoted prostate cancer cell proliferation. ⺠Osteonectin-null bone matrix promoted resistance to radiation-induced cell death. ⺠Osteonectin may suppress prostate cancer pathogenesis in the skeletal microenvironment.
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Authors
Kristina Kapinas, Katie M. Lowther, Catherine B. Kessler, Karissa Tilbury, Jay R. Lieberman, Jennifer S. Tirnauer, Paul Campagnola, Anne M. Delany,