PEA3 transcription factors are downstream effectors of Met signaling involved in migration and invasiveness of Met-addicted tumor cells

•Integration of the Met receptor signaling at the transcriptional level is poorly understood.•In cancer cells harboring met gene amplification, expression of ETV1, 4 and 5 is dependent of the receptor activity.•PEA3 factors are required for efficient migration and invasion mediated by Met, while other responses remain unaffected.•The three PEA3 factors are key players of the Met signaling integration involved in regulation of migration and invasiveness.