| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2145645 | Molecular Oncology | 2011 | 10 Pages |
Abstract
ⶠSurvivin promoter-regulated oncolytic adenovirus AdSurp-P53 is recombined. ⶠThe oncolytic adenovirus has a high proliferation activity in gallbladder cancer. ⶠThe oncolytic adenovirus mediates high P53 expression in gallbladder cancer cells. ⶠAdSurp-P53 possesses a stronger cytotoxic effect against gallbladder cancer cells. ⶠAdSurp-P53 inhibits xenograft tumor growth in nude mice by inducing cell apoptosis.
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Authors
Chen Liu, Bin Sun, Ni An, Weifeng Tan, Lu Cao, Xiangji Luo, Yong Yu, Feiling Feng, Bin Li, Mengchao Wu, Changqing Su, Xiaoqing Jiang,