| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2145992 | Molecular Oncology | 2011 | 12 Pages |
Abstract
⺠Centrosome abnormalities occur commonly in cancer. ⺠Centrosome clustering enables cells with extra centrosomes to divide successfully. ⺠We discuss the molecular basis of centrosome clustering and its biological roles. ⺠Clustering impacts on stem cell division, chromosomal stability and tumorigenesis. ⺠Inhibition of centrosome clustering promises to selectively target tumor cells.
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Authors
Alwin Krämer, Bettina Maier, Jiri Bartek,