Article ID Journal Published Year Pages File Type
2146181 Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2016 6 Pages PDF
Abstract
Using a zinc finger nuclease (ZFN) that creates a site-specific DNA double-strand break (DSB) at the endogenous ADH1 locus, we provide genetic evidence that histone H2AX and DSB-induced small RNAs modulate DNA repair by both non-homologous end-joining (NHEJ) and homologous recombination (HR) in the model plant Arabidopsis thaliana.
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Histone H2AX and the small RNA pathway modulate both non-homologous end-joining and homologous recombination in plants
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