Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2146369 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2014 | 8 Pages |
Abstract
This study shows that the ERCC1 C118T variants are not associated with survival in ACC patients treated with oxaliplatin or the in vitro sensitivity and DNA-repair capacity in 118C and 118T transfected cell lines. Therefore, ERCC1 C118T genotyping seems of no value in individualizing oxaliplatin based chemotherapy in ACC.
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Authors
Lieke H. van Huis-Tanja, Dina M. Kweekel, Xiaobo Lu, Kees Franken, Miriam Koopman, Hans Gelderblom, Ninja F. Antonini, Cornelis J.A. Punt, Henk-Jan Guchelaar, Tahar van der Straaten,