Article ID Journal Published Year Pages File Type
2146752 Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2010 8 Pages PDF
Abstract

Fpg protein from Escherichia coli belongs to the class of DNA glycosylases/abasic site lyases excising several oxidatively damaged purines in the base excision repair pathway. In this review, we summarize the results of our studies of Fpg protein from E. coli, elucidating the intrinsic mechanism of recognition and excision of damaged bases in DNA.

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