| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2146975 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2009 | 6 Pages |
Abstract
RecBCD and RecFOR homologous recombination pathways induced bacterial chromosomal duplication–segregation by sodium selenite (SSe) at sub-inhibitory concentrations. This evidence suggests that SSe induces both, double and single DNA strand damage with a concomitant DNA repair response, however the strong dependence for recombinogenic activity of RecB product suggests that the main DNA repair pathway copes with dsDNA breaks. A role for SSe recombinogenic induction is proposed to explain its effect on DNA instability.
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Authors
Javier Espinosa-Aguirre, Claudia Barajas-Lemus, Sandra Hernández-Ojeda, Tzipe Govezensky, Julieta Rubio, Rafael Camacho-Carranza,