Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2147995 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2014 | 9 Pages |
Abstract
Cancer is a complex disease involving a sequence of gene-environment interactions. Lifestyle, genetics, dietary factors, and environmental pollutants can increase the risk of cancer. Gene-environment interactions have been studied by a candidate-gene approach focusing on metabolism, DNA repair, and apoptosis. Here, we review the influence of gene-environment interactions in carcinogenesis, with emphasis on heavy metal and pesticide exposures.
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Authors
Shams Tabrez, Medha Priyadarshini, Shubha Priyamvada, Mohd Shahnawaz Khan, Arivarasu NA, Syed Kashif Zaidi,