Article ID Journal Published Year Pages File Type
2148085 Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2013 10 Pages PDF
Abstract
► Bisphenol A (BPA) disrupts all microtubule arrays in Pisum sativum (pea). ► Cell cycle and chromosome abnormalities are attributed to microtubule disruption. ► Dissimilar to animal cells, BPA induces the formation of bipolar pointed spindles. ► Microtubule dynamics are suppressed and macrotubules are formed. ► Macrotubules may constitute a defensive response to BPA toxicity.
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