Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2148085 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2013 | 10 Pages |
Abstract
⺠Bisphenol A (BPA) disrupts all microtubule arrays in Pisum sativum (pea). ⺠Cell cycle and chromosome abnormalities are attributed to microtubule disruption. ⺠Dissimilar to animal cells, BPA induces the formation of bipolar pointed spindles. ⺠Microtubule dynamics are suppressed and macrotubules are formed. ⺠Macrotubules may constitute a defensive response to BPA toxicity.
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Authors
Ioannis-Dimosthenis S. Adamakis, Emmanuel Panteris, Anna Cherianidou, Eleftherios P. Eleftheriou,