Article ID Journal Published Year Pages File Type
2148277 Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2011 7 Pages PDF
Abstract
► An improved hydroxyl radical cleavage protocol has been developed. ► The structures of AC and CC mismatches have been investigated by the new protocol. ► The structures of minor groove binder-DNA complexes have also been investigated. ► The cleavage results are consistent with predictions from crystal structures. ► The presence of an AC or CC mismatch has been found to alter minor groove binding.
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