Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2148277 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2011 | 7 Pages |
Abstract
⺠An improved hydroxyl radical cleavage protocol has been developed. ⺠The structures of AC and CC mismatches have been investigated by the new protocol. ⺠The structures of minor groove binder-DNA complexes have also been investigated. ⺠The cleavage results are consistent with predictions from crystal structures. ⺠The presence of an AC or CC mismatch has been found to alter minor groove binding.
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Authors
Dobroslawa Bialonska, Kenneth Song, Philip H. Bolton,