| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 214934 | The Journal of Chemical Thermodynamics | 2016 | 8 Pages |
•The solubility data of pyraclostrobin in pure and binary solvents were determined and correlated.•The theory of solubility parameter was used to explain the cosolvency in binary solvents.•A modified mixing rule was proposed to calculate the solubility parameter of binary solvents.•The dissolution thermodynamic properties were calculated and discussed.
The solubility of pyraclostrobin in five pure solvents and two binary solvent mixtures was measured from 283.15 K to 308.15 K using a static analytical method. Solubility in five pure solvents was well correlated by the modified Apelblat equation and Wilson model. While the CNIBS/R–K model was applied to correlate the solubility in two binary solvent mixtures, the correlation showed good agreement with experimental results. The solubility of pyraclostrobin reaches its maximum value at a certain cyclohexane mole fraction in the two binary solvent mixtures. The solubility parameter of pyraclostrobin was calculated by the Fedors method and a new modified mixing rule with preferable applicability was proposed to determine the solubility parameter of solvents. Then the co-solvency in the binary solvent mixtures can be explained based on the obtained solubility parameters. In a addition, the dissolution thermodynamic properties were calculated from the experimental values using the Wilson model.
