| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2149723 | Mutation Research/Reviews in Mutation Research | 2009 | 8 Pages |
Abstract
DNA acts as a ‘workbench’ for various nuclear processes that occur inside living cells. In eukaryotic cells, DNA is highly compacted in a structural hierarchy with histones and other proteins into chromatin. This compaction affects DNA structure and coordinates the accessibility to site-specific nuclear factors during DNA processing events. DNA repair is no exception to this general rule and several reviews have appeared recently that discuss this topic in detail [1], [2] and [3]. Here, we focus on recent findings correlating changes in DNA repair with subtle variations in the chromatin landscape.
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Authors
Ronita Nag, Michael J. Smerdon,