Langerhans cell histiocytosis in the jugular foramen

Langerhans cell histiocytosis (LCH) is a rare disease of neoplastic proliferation of monocyte–macrophage system. Although LCH can affect almost any organ, solitary involvement of jugular foramen is extremely rare and can present a diagnostic dilemma because of its rarity at this location. Here, we present the case of an adult patient with LCH affecting the jugular foramen, and review the relevant literature.